Thermo Fisher Scientific UFD1L Monoclonal Antibody (OTI5E3), TrueMAB
Thermo Fisher Scientific의 UFD1L 단클론 항체(OTI5E3)는 인간 UFD1L 단백질을 특이적으로 인식하며 Western blot에 적합합니다. 고순도의 액상 항체로 PBS, BSA, 글리세롤로 안정화되어 있으며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific UFD1L Monoclonal Antibody (OTI5E3), TrueMAB
Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E3 |
| Immunogen | Full length human recombinant protein of human UFD1L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ubiquitin-mediated proteolysis requires the transfer of ubiquitin (Ub) to lysine groups on selected cellular proteins, promoting their degradation by the 26S proteasome. Ub-fusions are cleaved by Ub-specific processing proteases (UBps) or by the Ub-fusion degradation (UFD) pathway.
The UFD1 protein, first identified in S. cerevisiae, has a human homolog known as UFD1 or UFD1L. In vitro, UFD1 attenuates degradation of Ub-fusions with specific amino acid substitutions at Gly76 through selective multiubiquitination.
Mutations in the UFD1 gene are associated with CATCH22 syndrome, characterized by cardiac defects, cleft palate, and hypocalcemia, suggesting a role of this pathway in developmental processes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.