Thermo Fisher Scientific BRD2 Recombinant Rabbit Monoclonal Antibody (JG40-42)
BRD2 단백질을 표적으로 하는 재조합 토끼 단일클론 항체. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합. 인간 시료 반응성. Protein A 정제, 1 mg/mL 농도. -20°C 보관, 동결/해동 반복 피할 것.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JG40-42 |
| Immunogen | Synthetic peptide within Human BRD2 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2848720 |
Product Specific Information
Positive Control: SiHa, 293T, A431, human tonsil tissue, human colon tissue.
Target Information
The BRD2 gene encodes a transcriptional regulator belonging to the BET (bromodomains and extra terminal domain) family of proteins. It associates with transcription complexes and acetylated chromatin during mitosis, selectively binding to acetylated lysine-12 residue of histone H4 via its two bromodomains.
This gene is located in the MHC class II region on chromosome 6p21.3 but is not directly involved in immune response. It has been implicated in juvenile myoclonic epilepsy. Multiple alternatively spliced variants exist, though some full-length forms are not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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