Thermo Fisher Scientific Neuropilin 1 Polyclonal Antibody
Thermo Fisher Scientific의 Neuropilin 1 Polyclonal Antibody는 Mouse 및 Rat 시료에 반응하는 Rabbit IgG 항체로, WB 및 IHC(P) 분석에 적합합니다. 액상 형태로 제공되며, 항원 친화 크로마토그래피로 정제되었습니다. 신경 및 심혈관 연구용으로 이상적입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of rat Neuropilin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792639 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%).
- Positive Control: Rat brain, mouse brain, mouse heart, rat heart.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Neuropilin 1 is a 923 amino acid membrane-bound coreceptor belonging to the neuropilin family, containing two CUB domains, two F5/8 type C domains, and a MAM domain. It forms a heterodimer with Neuropilin 2 (NRP2) and binds to plexin (PLXNB1) to form semaphorin receptors.
Expressed mainly in the nervous system, Neuropilin 1 is involved in cardiovascular development, angiogenesis, axon guidance, neuronal circuit formation, cell survival, neuronal migration, and organogenesis. It functions as a receptor for semaphorins and VEGF, regulating VEGF-induced angiogenesis. Neuropilin 1 may also play roles in aggressive prostate carcinoma and breast cancer progression.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-85499_Neuropilin_1_CD304_Q9QWJ9-1_Rabbit.svg, PA5-85499_Neuropilin_1_CD304_Q9QWJ9-1_Rabbit_PDP.jpeg)
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