Thermo Fisher Scientific Iduronate 2 Sulfatase Polyclonal Antibody
Iduronate 2 Sulfatase 단백질을 인식하는 Thermo Fisher의 염소 폴리클로날 항체. Western blot과 IHC(P)에서 사용 가능. 합성 펩타이드 면역원 기반으로 제작되었으며, 0.5 mg/mL 농도의 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KHFRFRDLEEDP) corresponding to internal amino acids of IDS (aa 440–452) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980527 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
Target Information
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate.
Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II (Hunter Syndrome).
Iduronate-2-sulfatase shows strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase.
Multiple alternatively spliced transcript variants encoding different protein isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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