Thermo Fisher Scientific TFIP11 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, and Chimpanzee.

Target Information

TFIP11 is involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover proceeds through two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15, it mediates the transition of the U2, U5, and U6 snRNP-containing IL complex to the snRNP-free IS complex, leading to efficient debranching and turnover of excised introns. It may also play a role in the differentiation of ameloblasts and odontoblasts or in the formation of the enamel extracellular matrix.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.