Thermo Fisher Scientific Calmodulin Polyclonal Antibody
Calmodulin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 적합. 고순도(>95%) 항체로 인간, 생쥐, 랫트에 반응. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 50–100 of Human Calmodulin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803299 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Calmodulin mediates the control of numerous enzymes, ion channels, aquaporins, and other proteins by Ca²⁺. The calmodulin–Ca²⁺ complex stimulates various protein kinases and phosphatases. Together with CCP110 and centrin, it participates in regulating the centrosome cycle and cytokinesis.
Calmodulin is a small, highly conserved calcium-binding protein found in all eukaryotic cells. It binds up to four calcium ions and acts as an intracellular receptor for regulatory calcium signals.
Upon calcium binding, calmodulin undergoes conformational changes that enhance its affinity for target proteins. It functions both directly and indirectly through kinases and is involved in processes such as energy metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of cAMP and calcium levels.
Calmodulin contains 149 amino acids and four calcium-binding domains, playing key roles in growth, cell cycle regulation, signal transduction, and neurotransmitter synthesis and release.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(원본에 명시된 항원 이미지: PA5-86525_Calmodulin_P0DP23-1_Rabbit.svg / PA5-86525_Calmodulin_P0DP23-1_Rabbit_PDP.jpeg)
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