Thermo Fisher Scientific USP11 Polyclonal Antibody
USP11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot 검증 완료. 인간 시료 반응성, 항원 친화 크로마토그래피로 정제. 액상 형태로 1 mg/mL 농도, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human USP11 (UniProt ID: P51784-1, Antigen range: 231–259) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635605 |
Product Specific Information
The antibody detects endogenous levels of total USP11 protein.
Target Information
USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the ubiquitin pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and the tumor suppressor BRCA2. Through these associations, USP11 functions to inhibit ubiquitination or to remove ubiquitin residues already attached to these proteins. USP11 is implicated in several X-linked retinal diseases and may play a role in tumor suppression due to its ability to deubiquitinate BRCA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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