Thermo Fisher Scientific PRMT1 Polyclonal Antibody
PRMT1 단백질을 인식하는 Rabbit Polyclonal Antibody로 다양한 응용(WB, IHC, IP)에 사용 가능. Human PRMT1(1-50aa) 영역을 면역원으로 제작. 비결합형 액상 형태로 4°C 보관. RNA 처리, 신호전달 및 전사 조절 연구에 적합.
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Thermo Fisher Scientific PRMT1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human Protein Arginine N-Methyltransferase 1 (PRMT1, UniProt ID: Q99873-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on sequence identity, antibody predicted to react with Rat
Target Information
PRMT1 is a member of the protein arginine N-methyltransferase (PRMT) family. Arginine methylation is an irreversible post-translational modification involved in RNA processing, receptor-mediated signaling, and transcription.
In mammals, at least three PRMT enzyme types have been identified, playing essential roles in regulating nuclear proteins, transcription factors, cell cycle proteins, and apoptosis-related proteins.
The mammalian PRMT family consists of seven members sharing two large homologous domains. Increased PRMT1 expression may be implicated in various cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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