Thermo Fisher Scientific PRMT1 Polyclonal Antibody
PRMT1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등 다양한 응용에 적합. Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 4°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- A300722A
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human Protein Arginine N-Methyltransferase 1 (PRMT1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat
Target Information
PRMT1 is a member of the protein arginine N-methyltransferase (PRMT) family. Arginine methylation is an irreversible post-translational modification implicated in RNA processing, receptor-mediated signaling, and transcription.
At least three types of PRMT enzymes have been identified in mammalian cells, which regulate key proteins involved in nuclear function, cell cycle, signal transduction, apoptosis, and viral processes.
The mammalian PRMT family consists of seven members sharing two large domains of homology. Increased expression of PRMT1 may be associated with various types of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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