
Thermo Fisher Scientific Human MAP3K7/MAP3K7IP1 (TAK1-TAB1), His Tag Recombinant Protein
인간 MAP3K7/MAP3K7IP1 (TAK1-TAB1) 재조합 단백질로, His-tag 부착 및 insect cell 발현 시스템 사용. 염증 반응과 세포 사멸 조절 연구에 활용 가능. 고순도(55%) 정제된 액상 형태로 -80°C에서 안정적으로 보관.
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Thermo Fisher Scientific Human MAP3K7/MAP3K7IP1 (TAK1-TAB1), His Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | 1–596 |
| Tag | His-tag |
| Molecular Weight | 45.8 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | 55% by SDS-PAGE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris (pH 7.5), 0.02% Triton X-100, 50% glycerol, 2 mM DTT, 0.5 mM EDTA, 150 mM NaCl |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- Spin briefly before use for maximum recovery.
- For 5 µg, 10 µg, and 20 µg sizes, use directly from original packaging.
- For larger sizes, aliquoting may reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
- Do not store kinase diluted.
- Stable for 6 months when stored at -80°C.
- Protein Form: Full Length
Target Information
MAP3K7 (TAK1) regulates transcription and apoptosis and is linked to inflammatory diseases and rheumatoid arthritis. Fusion with MAP3K7IP1 (TAB1) activates MAP3K7. TAK1 interacts with TGF-β receptor and TRAF6 to modulate activation of JNK and p38, and participates in Wnt, BMP, activin, and thyroid hormone signaling. TAB1 serves as a regulator and activator of TAK1 kinase involved in TGF-β, IL-1, and WNT-1 signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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