Thermo Fisher Scientific DYNC1I2 Polyclonal Antibody
DYNC1I2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. Human 및 Mouse 반응성 확인. 항원 친화 크로마토그래피로 정제된 액상 항체로 4°C 단기, -20°C 장기 보관 권장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific DYNC1I2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment containing a sequence corresponding to amino acids 129–366 (Q13409) of DYNC1I2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11154571 |
Product Specific Information
- Recommended positive controls: HeLa
- Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (93%), Pig (98%), Chicken (94%), Rhesus Monkey (100%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into mechanical energy of movement.
Cytoplasmic or axonemal Dynein heavy, intermediate, light, and light-intermediate chains are components of minus end-directed motors, transporting cellular cargos toward the cell center.
Axonemal Dynein motors contain one to three non-identical heavy chains and cause sliding of microtubules in the axonemes of cilia and flagella, enabling ciliary motion.
Cytoplasmic Dynein is a ~12 subunit complex including two heavy chains, two intermediate chains anchoring Dynein to cargo, four smaller intermediate chains, and several light chains.
It is essential for organelle transport, centrosome assembly, and other cellular functions.
The carboxy-terminus is conserved for microtubule-dependent motility, while the amino-terminal regions are variable.
Dynein activity is regulated by proteins such as Dynactin, LIS1, and nudel (nudE-like).
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.