Thermo Fisher Scientific NPHP4 Polyclonal Antibody
Human NPHP4 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 최적화됨. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 액상 형태, 1 mg/mL 농도, -20°C 보관.
- 카탈로그번호
- PA550072
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human NPHP4 (UniProt ID: O75161-1, antigen range: 877–926, antigen length: 1426) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635525 |
Product Specific Information
This antibody detects endogenous levels of total NPHP4 protein.
Target Information
The NPHP4 gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin and forms part of a multifunctional complex localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and Senior-Loken syndrome type 4, which combines nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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