Thermo Fisher Scientific hnRNP H2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Immunogen sequence:
DGRVTGEADV EFATHEDAVA AMAKDKANMQ HRYVELFLNS TAGTSGGAYD HSYVELFLNS TAGASGGAYG SQMMGGMGLS NQSSYGGPAS QQLSGGYGGG YGGQSSMSGY DQVLQ

Target Information

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein.
[Provided by RefSeq]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.