Thermo Fisher Scientific CD45 Monoclonal Antibody (2D1), PerCP-Cyanine5.5, eBioscience
인간 CD45 모든 아이소폼을 인식하는 2D1 모노클론 항체로, PerCP-Cyanine5.5 형광체가 결합되어 있습니다. 유세포분석(Flow Cytometry)에 최적화되어 있으며, 5 µL/test로 사용됩니다. 488 nm 여기, 695 nm 방출 특성. 연구용으로만 사용 가능합니다.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD45 Monoclonal Antibody (2D1), PerCP-Cyanine5.5, eBioscience
Thermo Fisher Scientific CD45 Monoclonal Antibody (2D1), PerCP-Cyanine5.5, eBioscience™
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.125 µg)/test
Publications: View 32 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PerCP-Cyanine5.5 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D1 |
| Conjugate | PerCP-Cyanine5.5 |
| Excitation/Emission Max | 489 / 679 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1548703 |
Additional Available Formats
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Brilliant Violet 711
- eFluor 450
- FITC
- NovaFluor Blue / Red / Violet / Yellow Series
- PE, PE-Cyanine7, PE-eFluor 610
- Super Bright Series (436, 600, 645, 780)
- Custom conjugation available upon request
Product Specific Information
The 2D1 monoclonal antibody reacts with all isoforms of human CD45, also known as Leukocyte Common Antigen (LCA). CD45 is expressed by all hematopoietic cells except circulating erythrocytes and platelets. The cytoplasmic portion of CD45 has tyrosine phosphatase enzymatic activity and plays an important role in lymphocyte activation.
- Applications Reported: Flow cytometric analysis
- Applications Tested: Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- Recommended Use: 5 µL (0.125 µg) per test (100 µL final volume)
- Excitation: 488 nm
- Emission: 695 nm
- Laser: Blue Laser
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase expressed in all nucleated hematopoietic cells, comprising about 10% of all surface proteins in lymphocytes. It is absent on non-hematopoietic cells and tissues. CD45 is critical for lymphocyte development and antigen signaling, regulating Src-family kinases and JAK kinases. Multiple isoforms exist due to alternative splicing, differing in extracellular domains but sharing transmembrane and cytoplasmic domains. CD45 also modulates integrin-mediated signaling, apoptosis, and various immunological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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