Thermo Fisher Scientific TXNDC4 Monoclonal Antibody (3C7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

ELISA (ELISA)

1 ng/mL

-

Immunoprecipitation (IP)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

3C7

Immunogen

TXNDC4 (AAH05374, 30 a.a. approximately 406 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ERP44,uniProtId:Q9BS26-1,ncbiNodeId:9606,antigenRange:30-406,antigenLength:406,antigenImageFileName:H00023071-M01_ERP44_Q9BS26-1_House_mouse.svg,antigenImageFileNamePDP:H00023071-M01_ERP44_Q9BS26-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: EITSLDTENI DEILNNADVA LVNFYADWCR FSQMLHPIFE EASDVIKEEF PNENQVVFAR VDCDQHSDIA QRYRISKYPT LKLFRNGMMM KREYRGQRSV KALADYIRQQ KSDPIQEIRD LAEITTLDRS KRNIIGYFEQ KDSDNYRVFE RVANILHDDC AFLSAFGDVS KPERYSGDNI IYKPPGHSAP DMVYLGAMTN FDVTYNWIQD KCVPLVREIT FENGEELTEE GLPFLILFHM KEDTESLEIF QNEVARQLIS EKGTINFLHA DCDKFRHPLL HIQKTPADCP VIAIDSFRHM YVFGDFKDVL IPGKLKQFVF DLHSGKLHRE FHHGPDPTDT APGEQAQDVA SSPPESSFQK LAPSEYRYTL LRDRDEL

Target Information

Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.