Thermo Fisher Scientific CCR3 Polyclonal Antibody
Human 및 비인간 영장류에 반응하는 CCR3 폴리클로날 항체로, Western blot, IHC, ELISA, IP 등 다양한 응용에 적합. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 제공되고 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1–50 on human CCR3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta.
CCR3 transduces a signal by increasing intracellular calcium ion levels and serves as an alternative co-receptor with CD4 for HIV-1 infection.
Chemokines are crucial for inflammation and recruitment of effector immune cells to infection sites. They activate leukocytes via G protein–coupled receptors.
Chemokine receptor subtypes are divided into two major groups: CXCR and CCR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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