Thermo Fisher Scientific Phospho-mTOR (Ser2448) Recombinant Rabbit Monoclonal Antibody (mTORS2448-E11), APC
APC 형으로 제공되는 Phospho-mTOR (Ser2448) 토끼 단클론 항체로, 인간 및 생쥐 시료에서 mTOR 신호전달 연구에 적합합니다. Flow cytometry에 최적화되어 있으며, 고순도 Protein A/G 정제 및 안정적 PBS/BSA 저장 조건을 갖습니다.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | mTORS2448-E11 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897327 |
Additional Formats
- Unconjugated (MA5-37144)
- FITC (MA5-37146)
- PE (MA5-37145)
- Custom conjugation available upon request
Target Information
FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene result in Smith-Kingsmore syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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