Thermo Fisher Scientific PRL3 Polyclonal Antibody
PRL3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에서 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around aa. 161–166 (K-D-P-H-T) derived from Human PRL-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2635129 |
Product Specific Information
This antibody detects transfected PRL3 protein.
Target Information
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are signaling molecules that regulate various cellular processes. This class of PTPs contains a PTP domain and a C-terminal prenylation motif. Studies in mice demonstrated that these proteins are prenylated in vivo and associated with the plasma membrane. Overexpression of this gene in mammalian cells inhibits angiotensin-II induced calcium mobilization and promotes cell growth. Two alternatively spliced variants exist. PRL-3 expression is upregulated in human liver carcinoma and may contribute to liver metastasis in colorectal cancer. It is also expressed in tumor metastasis and vasculature regardless of tumor source.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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