Thermo Fisher Scientific ERCC1 Monoclonal Antibody (OTI3G5), TrueMAB
ERCC1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot과 Flow cytometry에 사용 가능. 인간 ERCC1 재조합 단백질을 면역원으로 제작. 동결건조 형태로 제공되며, PBS/trehalose 버퍼에 보존. DNA 복구 관련 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G5 |
| Immunogen | Full length human recombinant protein of human ERCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair. It functions with SLX4 in the initial step of interstrand cross-link (ICL) repair and participates in the processing of DNA structures that can lead to cytokinesis failure. ERCC1 also plays a role in homology-directed repair (HDR) of DNA double-strand breaks in conjunction with SLX4. (Source: Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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