Thermo Fisher Scientific Diaphanous 1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Diaphanous Homolog 1 (DIAPH1). Suitable for IHC and IHC (Paraffin) applications. Affinity-purified, liquid form, stored at 4°C. Predicted cross-reactivity with primates. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1200 and the C-terminus (residue 1248) of human Diaphanous Homolog 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Orangutan, Gorilla, and Northern white-cheeked gibbon
Target Information
This gene is a homolog of the Drosophila diaphanous gene and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss.
Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It is speculated that this gene may play a role in regulating actin polymerization in hair cells of the inner ear.
Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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