Thermo Fisher Scientific BIRC7 Monoclonal Antibody (OTI1B10), TrueMAB
인간 BIRC7 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, ICC/IF, Flow cytometry에 사용 가능. TrueMAB 포맷으로 높은 특이성과 재현성을 제공하며, 연구용으로만 사용됨. -20°C에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B10 |
| Immunogen | Full length human recombinant protein of human BIRC7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif essential for anti-apoptotic activity. A novel human IAP family member, Livin (ML-IAP), contains a single BIR domain and a COOH-terminal RING finger domain. Livin has two splicing variants (298 and 280 amino acids), both containing BIR and RING domains. These isoforms inhibit TNFα-induced apoptosis in Jurkat cells. Livin expression is low in adult tissues but relatively higher in developmental tissues and many cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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