Thermo Fisher Scientific BIRC7 Monoclonal Antibody (OTI1D12), TrueMAB
인간 BIRC7 단백질을 인식하는 마우스 단클론 항체로 Western blot, IHC, Flow cytometry 등에 사용 가능. 고순도 친화 크로마토그래피 정제. PBS/BSA/glycerol 완충액에 보존되며 -20°C에서 안정적 저장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D12 |
| Immunogen | Full length human recombinant protein of human BIRC7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.36 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity.
A novel human IAP family member termed Livin (ML-IAP) contains a single baculoviral IAP repeat (BIR) domain and a COOH-terminal RING finger domain.
Livin gene has two splicing variants (298 and 280 amino acids) that both inhibit TNFα-induced apoptosis in Jurkat cells.
Livin expression is low in adult tissues but relatively higher in developmental tissues and many cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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