Thermo Fisher Scientific MMP7 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal MMP7 항체로 WB와 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제된 고순도 제품. 세포외기질 분해 관련 연구 및 MMP7 기능 분석에 활용 가능. 연구용 한정.
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Applications
- Western Blot (WB): 1:500–1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 211–260 of Human MMP-7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802978 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes like arthritis and metastasis.
Most MMPs are secreted as inactive proproteins and activated by extracellular proteinases.
The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin, and casein, and differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
It is involved in wound healing and may regulate defensin activity in intestinal mucosa.
The gene is part of a cluster of MMP genes localized to chromosome 11q22.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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