Thermo Fisher Scientific EphB6 Polyclonal Antibody
EphB6 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot과 ELISA에 적합하며, 고순도의 Affinity Chromatography 정제 제품입니다. PBS/glycerol buffer에 보관되며, -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 615–729 of human EPHB6 (NP_001267724.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.51 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913861 |
Product Specific Information
- Positive test controls: U-251MG, BxPC-3, Mouse thymus, Mouse brain
- Subcellular localization: Membrane, Secreted, Single-pass type I membrane protein
Immunogen sequence:
HFDQLVAAFD KMIRKPDTLQ AGGDPGERPS QALLTPVALD FPCLDSPQAW LSAIGLECYQ DNFSKFGLCT FSDVAQLSLE DLPALGITLA GHQKKLLHHI QLLQQHLRQQ GSVEV
Target Information
Ephrin receptors and their ligands (ephrins) mediate numerous developmental processes, particularly in the nervous system.
Ephrins are divided into two classes: ephrin-A (EFNA), which are GPI-anchored, and ephrin-B (EFNB), which are transmembrane proteins.
The Eph receptor family is the largest subgroup of receptor tyrosine kinases (RTKs), divided based on extracellular domain similarity and ligand affinity.
The EphB6 receptor lacks kinase activity but binds ephrin-B ligands.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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