Thermo Fisher Scientific RNF3 Polyclonal Antibody
RNF3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 검증 완료. 인간 단백질에 반응하며, Protein A로 정제된 액상 형태. 연구용으로만 사용 가능.
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Thermo Fisher Scientific RNF3 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human PCGF3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607603 |
Product Specific Information
- Peptide sequence:
EVPGDIKGET CSAKQHLDSH RNGETKADDS SNKEAAEEKP EEDNDYHRSD - Sequence homology:
Cow: 86%
Dog: 93%
Guinea Pig: 79%
Horse: 79%
Human: 100%
Mouse: 86%
Pig: 86%
Rabbit: 85%
Rat: 86%
Yeast: 75%
Target Information
Phosphorylase kinase is a hexadecameric enzyme composed of four copies of four subunits encoded by the PHKA, PHKB, PHKG, and PH genes. This serine/threonine-specific kinase converts glycogen phosphorylase b to glycogen phosphorylase a, releasing glucose-1-phosphate from glycogen.
PHKB (Phosphorylase b kinase regulatory subunit beta) is a 1093 amino acid subunit with regulatory functions controlled by phosphorylation. Mutations in PHKB cause glycogen storage disease type 9B, characterized by mild hepatomegaly, slightly elevated transaminase and plasma lipids, no muscle involvement, and gradual improvement with age.
Four isoforms of PHKB exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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