Thermo Fisher Scientific TYW1B Polyclonal Antibody
Human TYW1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P)에서 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 용액에 40% 글리세롤 포함. 단기 4°C, 장기 -20°C 보관 권장.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TYW1. Recombinant protein control fragment (Product #RP-102540). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649151 |
Product Specific Information
Immunogen sequence:
KEQQEEKSGL FRNMGRNEDG ERRAMITPAL REALTKQVDA PRERSLLQTH ILW
Highest antigen sequence identity to the following orthologs:
- Mouse: 45%
- Rat: 49%
Target Information
Wybutosine is a hypermodified guanosine found in phenylalanine tRNA. It functions to stabilize codon-anticodon interactions during ribosome decoding and supports maintenance of the reading frame. In yeast, the homolog of this gene is essential for wybutosine synthesis. The human genome contains two closely related genes that putatively function in wybutosine synthesis. The open reading frame of this locus is disrupted in some individuals, suggesting it may be an evolving pseudogene but potentially functional in some populations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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