
Thermo Fisher Scientific SRY Polyclonal Antibody
Rabbit polyclonal antibody specific to human SRY protein. Validated for Western blot with high specificity. Supplied as liquid form at 0.5 mg/mL. Suitable for research on sex determination and SRY gene expression. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SRY |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2884114 |
Product Specific Information
- Immunogen sequence: SEVQLDNRLY RDDCTKATHS RMEHQLGHLP PINAASSPQQ RDRYSHWTKL
- Storage guidance:
- Short-term: Store at 2–8°C for up to 1 week
- Long-term: Store at -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology:
- Human: 100%
- Rat: 93%
Target Information
This intronless gene encodes a transcription factor belonging to the high mobility group (HMG)-box family of DNA-binding proteins. The SRY protein acts as the testis-determining factor (TDF), initiating male sex determination. Mutations in this gene can result in XY females with gonadal dysgenesis (Swyer syndrome), while translocation of the Y chromosome segment containing this gene to the X chromosome can cause XX male syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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