Thermo Fisher Scientific PREP Polyclonal Antibody
Human PREP 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200–1:500 희석으로 검증됨. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 연구용으로만 사용 가능하며 장기 보관 시 -20°C에서 냉동 보관 권장.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PREP. Recombinant protein control fragment (Product #RP-94646) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645931 |
Product Specific Information
Immunogen sequence:
IACVRSNFLV LCYLHDVKNI LQLHDLTTGA LLKTFPLDVG SIVGYSGQKK DTEIFYQFTS FLSPGIIYHC DLTKEELEPR VFREVTVKGI DASDY
- Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 92%
Target Information
p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase.
Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important for the progression from G1 to S-phase.
The levels of cyclin A-cdk2 are maximal at the G1/S transition, and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication.
Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo.
Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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