Thermo Fisher Scientific PSCA Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human PSCA(Accession O43653), corresponding to amino acid residues A51-Q101. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PSCA,uniProtId:O43653-1,ncbiNodeId:9606,antigenRange:51-101,antigenLength:114,antigenImageFileName:PA5-115799_PSCA_O43653-1_Rabbit.svg,antigenImageFileNamePDP:PA5-115799_PSCA_O43653-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2900434

Product Specific Information

Antibody detects endogenous levels of total Prostate Stem Cell Antigen.

Target Information

PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in approximately40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.