Thermo Fisher Scientific FAM62B Monoclonal Antibody (C4-D0)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

C4-D0

Immunogen

Recombinant protein within human FAM62B aa 300-550 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FAM62B,uniProtId:A0FGR8-1,ncbiNodeId:9606,antigenRange:300-550,antigenLength:921,antigenImageFileName:MA5-42563_FAM62B_A0FGR8-1_House_mouse.svg,antigenImageFileNamePDP:MA5-42563_FAM62B_A0FGR8-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein G

Storage buffer

TBS, pH 7.4, with 50% glycerol, 0.2% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2911704

Product Specific Information

Positive Control: Siha cell lysate, THP-1 cell lysate, human colon carcinoma tissue.

Subcellular Location: Cell membrane, Endoplasmic reticulum, Membrane.

Target Information

Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS) (PubMed:27044890). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.