Thermo Fisher Scientific TMEM259 Polyclonal Antibody
TMEM259 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 0.2 mg/mL 농도의 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TMEM259. Recombinant protein control fragment (Product #RP-106573) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663468 |
Product Specific Information
Immunogen sequence:
AAGGDLGWMAE TAAIITDASF LSGLSASLLE RRPASPLGPA GGLPHAPQDS VPPSDSAASD TTPLGAAVGG PSPASM
Highest antigen sequence identity to the following orthologs:
- Mouse: 47%
- Rat: 49%
Target Information
Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species.
The membralin gene contains 11 exons which encode at least two spliced variants in human cancer.
- Membralin-1 (long form): 620 amino acids, includes all 11 exons.
- Membralin-3 (short form): 408 amino acids, lacks exon 10.
Expression of different membralin isoforms depends on tissue type:
- Membralin-1: expressed in ovarian and colorectal carcinomas
- Membralin-3: expressed in breast and pancreatic carcinomas
Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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