
Thermo Fisher Scientific HEYL Monoclonal Antibody (OTI4D8), TrueMAB
HEYL 단백질을 인식하는 Mouse IgG2b 단일클론 항체로 Western blot에 적합. 인간 시료 반응성, 무보존제, 동결건조 형태. 재구성 후 1 mg/mL 농도로 사용 가능하며, Notch 신호 경로 관련 연구에 활용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D8 |
| Immunogen | Full length human recombinant protein of human HEYL produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
HEYL is a member of the HESR family of basic helix-loop-helix (bHLH)-type transcription factors. The protein contains conserved bHLH and orange domains, but its YRPW motif has diverged from other HESR members. It functions as an effector of Notch signaling and regulates cell fate decisions.
Alternative splicing variants have been identified, though their biological significance remains unclear.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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