Thermo Fisher Scientific ING3 Monoclonal Antibody (2E21)
ING3 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 단백질에 반응하며, 액상 형태로 제공됩니다. 암 연구 및 세포 성장 조절 관련 연구에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E21 |
| Immunogen | ING3 (NP_938008, 1 a.a. ~ 92 a.a) partial recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MLYLEDYLEM IEQLPMDLRD RFTEMREMDL QVQNAMDQLE QRVSEFFMNA
KKNKPEWREE QMASIKKDYY KALEDADEKV QLANQIYDLQ HFTarget Information
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis.
This protein contains a PHD-finger, a motif common in chromatin remodeling proteins.
It can activate p53 trans-activated promoters such as p21/waf1 and bax.
Overexpression inhibits cell growth and induces apoptosis.
Allelic loss and reduced expression have been detected in head and neck cancers.
Two alternatively spliced transcript variants encoding different isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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