Thermo Fisher Scientific U2AF1L4 Polyclonal Antibody
U2AF1L4 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 적합하며 인간에 반응하고, 개, 생쥐, 랫드에서도 예측 반응. 액상 형태, 0.5 mg/mL 농도, -20°C 보관.
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Applications
- Western Blot (WB): 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (EDGERAVAELSNR) corresponding to the internal amino acids of U2AF1L4 (aa 121–134) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983829 |
Product Specific Information
- Predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
RNA-binding protein functioning as a pre-mRNA splicing factor. Plays a critical role in constitutive and enhancer-dependent splicing by mediating protein–protein and protein–RNA interactions required for accurate 3′-splice site selection. Enhances U2AF2 binding to weak pyrimidine tracts and participates in alternative pre-mRNA splicing regulation. Activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. Binds RNA at the AG dinucleotide at the 3′-splice site, showing preference for AGC or AGA. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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