Thermo Fisher Scientific SS18 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal 항체로 SYT 단백질을 검출합니다. Western blot에 사용 가능하며, 액상 형태로 1 mg/mL 농도입니다. PBS/glycerol buffer에 보관되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around aa.14–18 (G-E-I-T-P) derived from Human SYT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2635131 |
Product Specific Information
The antibody detects endogenous levels of total SYT protein.
Target Information
The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino-terminal SNH domain and a carboxy-terminal QPGY domain, which functions as a transcriptional activating sequence.
Synovial sarcoma translocation (SSX) proteins (SSX1–5) are transcriptional repressors containing a repressor domain in their carboxy termini.
SSX proteins are localized to the nucleus and expressed in testis and several types of cancers, thus classified as C/T (cancer/testis) antigens.
The t(x;18) translocation fuses the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2, producing transcriptional activators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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