Thermo Fisher Scientific TIA-1 Monoclonal Antibody (2A10B12)
Human TIA-1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC, Flow, ELISA 등 다양한 응용에 적합. Protein G로 정제된 액상 형태로 1 mg/mL 농도 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TIA-1 Monoclonal Antibody (2A10B12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A10B12 |
| Immunogen | Purified recombinant fragment of human TIA1 (AA: 1–215) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3090862 |
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through signals from WNT3A to stabilize beta-catenin and Noggin, a bone morphogenetic protein inhibitor. Mutations in Noggin are associated with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), characterized by multiple joint fusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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