Thermo Fisher Scientific TSPAN8 Monoclonal Antibody (8A4A10)
TSPAN8 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC, Flow, ELISA 등 다양한 응용에 사용 가능. Human 시료에 반응하며 Protein G로 정제된 액상 형태. 암 관련 연구 및 세포 신호전달 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8A4A10 |
| Immunogen | Purified recombinant fragment of human TSPAN8 (AA: Extra(110–205)) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090907 |
Target Information
TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237 amino acid multi-pass membrane protein belonging to the tetraspanin family. It is involved in signal transduction events that influence cell development, activation, growth, and motility. Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal, and pancreatic cancers, suggesting a role in cancer formation and metastasis. The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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