Thermo Fisher Scientific NAPSA Polyclonal Antibody
인간 및 생쥐 NAPSA 단백질을 검출하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 정제 방식으로 제조되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human napsin A aspartic peptidase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2635782 |
Product Specific Information
This antibody detects endogenous levels of total Napsin A protein.
Target Information
Napsin 1 is an aspartic protease predominantly expressed in the lung, and also found in kidney and metastatic carcinomas. It processes surfactant protein B in pulmonary and renal tissues but is dysregulated during carcinogenesis. Napsin evaluation assists in identifying various cancers and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, it serves as a specific biomarker for carcinoma type differentiation. Additionally, Napsin has been linked to pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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