Thermo Fisher Scientific PC4 Polyclonal Antibody
PC4 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, IP 등에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 인체 및 마우스 반응성. 4°C 보관, 1년 안정성 보장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 77 and 127 of human positive cofactor 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Chicken, and Orangutan
Target Information
PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator that can suppress promoter-driven and nonspecific transcription via its DNA binding activity.
The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH, which protects promoters from PC4-mediated repression through the ERCC3 helicase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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