Thermo Fisher Scientific FGFR1OP Polyclonal Antibody
FGFR1OP 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot과 IHC(Paraffin) 실험에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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- PA549739
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human FGFR1 Oncogene Partner |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635192 |
Product Specific Information
This antibody detects endogenous levels of total FGFR1OP protein.
Target Information
The FGFR1OP gene encodes a largely hydrophilic protein, considered a member of the leucine-rich protein family. A chromosomal translocation t(6;8)(q27;p11) fusing FGFR1OP and FGFR1 has been observed in myeloproliferative disorders. The resulting chimeric protein combines the N-terminal leucine-rich region of FGFR1OP with the catalytic domain of FGFR1. This gene is implicated in normal proliferation and differentiation of erythroid lineage cells. Alternatively spliced transcript variants encoding different proteins have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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