Thermo Fisher Scientific mGluR4 Polyclonal Antibody
mGluR4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며, -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human GluR4 (mGluR4, UniProt ID: Q14833-1, antigen range: 869–891) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635194 |
Product Specific Information
This antibody detects endogenous levels of total mGluR4 protein.
Target Information
The Metabotropic Glutamate Receptor mGluR4 (GRM4) binds L-glutamate, the major excitatory neurotransmitter in the central nervous system. It activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is essential for normal brain function and can be altered in various neuropathologic conditions. Metabotropic glutamate receptors are G protein-coupled receptors classified into three groups based on sequence homology, signaling mechanisms, and pharmacologic properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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