Thermo Fisher Scientific ANKRD13A Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:10,000–1:25,000

Immunoprecipitation (IP)

• Tested Dilution: 50–100 µL/mg of lysate

Product Specifications

Target Information

ANKRD13A (also known as ANKRD13) is a 590 amino acid protein containing two ANK repeats and four UIM (ubiquitin-interacting motif) repeats. It localizes to the cell membrane and functions as a ubiquitin-binding protein that specifically recognizes and binds Lys-63-linked ubiquitin, but not Lys-48-linked ubiquitin. ANKRD13A positively regulates the internalization of ligand-activated EGFR by binding to the ubiquitinated EGFR at the cell membrane.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.