Thermo Fisher Scientific SERCA2 Polyclonal Antibody
SERCA2 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 다양한 종에 교차 반응. 항원 친화 크로마토그래피로 정제된 액상 시약으로 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 475 and 525 of Human ATPase, Ca++ transporter, cardiac muscle, slow twitch 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, Rat, Chicken, Dog, Rabbit, Pig, and Cat
Target Information
This gene encodes one of the SERCA Ca(2+)-ATPases, intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells.
The enzyme catalyzes ATP hydrolysis coupled with calcium translocation from the cytosol into the sarcoplasmic reticulum lumen, regulating the contraction/relaxation cycle.
Mutations in this gene cause Darier-White disease (keratosis follicularis), an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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