Thermo Fisher Scientific Phospho-MEK1 (Ser298) Recombinant Rabbit Monoclonal Antibody (MEK1S298-H8), FITC
인산화 MEK1(Ser298)을 특이적으로 인식하는 FITC 결합 재조합 토끼 단클론 항체. 인간 및 랫트 반응성. Flow Cytometry에 적합하며, 단백질 A/G 정제 및 PBS+BSA 완충액에 보관. 연구용으로만 사용.
- 카탈로그번호
- MA537328
- 판매단위
- pk
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Thermo Fisher Scientific Phospho-MEK1 (Ser298) Recombinant Rabbit Monoclonal Antibody (MEK1S298-H8), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MEK1S298-H8 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser298 of human phospho MEK1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897262 |
Additional Formats
- Unconjugated
- APC
- PE
- Custom conjugation available
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx. MEK1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. It is involved in stress response signaling, apoptosis, and cytokine-induced proliferation. Mutations in the gene can lead to cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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