Thermo Fisher Scientific Phospho-Akt1 (Ser473) Recombinant Rabbit Monoclonal Antibody (AktS473-B9), FITC
FITC 결합형 Phospho-Akt1 (Ser473) 재조합 토끼 단클론 항체로, 인간 및 생쥐 시료에 반응합니다. Flow Cytometry에 적합하며, 세포 생존 및 신호전달 연구에 활용됩니다. 고순도 Protein A/G 정제, 4°C 암조건 보관.
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Thermo Fisher Scientific Phospho-Akt1 (Ser473) Recombinant Rabbit Monoclonal Antibody (AktS473-B9), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | AktS473-B9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser473 of human phospho Akt1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, store in dark |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897258 |
Additional Formats
- Unconjugated ([MA5-37062])
- PE ([MA5-37063])
- Request custom conjugation (Thermo Fisher form)
Target Information
AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival. The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells. This protein kinase is activated by insulin, PI3K, IGF1, and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors and caspase-9. The AKT pathway is a major target for cancer drug discovery.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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