Thermo Fisher Scientific ATP1B3 Monoclonal Antibody (2F4)

Applications

• ELISA (ELISA)
  Tested Dilution: 0.03 ng/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MTKNEKKSLN QSLAEWKLFI YNPTTGEFLG RTAKSWGLIL LFYLVFYGFL AALFSFTMWV MLQTLNDEVP KYRDQIPSPG LMVFPKPVTA LEYTFSRSDP TSYAGYIEDL KKFLKPYTLE EQKNLTVCPD GALFEQKGPV YVACQFPISL LQACSGMNDP DFGYSQGNPC ILVKMNRIIG LKPEGVPRID CVSKNEDIPN VAVYPHNGMI DLKYFPYYGK KLHVGYLQPL VAVQVSFAPN NTGKEVTVEC KIDGSANLKS QDDRDKFLGR VMFKITARA

Target Information

The protein encoded by ATP1B3 belongs to the family of Na⁺/K⁺ and H⁺/K⁺ ATPases beta chain proteins, specifically the Na⁺/K⁺-ATPase subfamily.
Na⁺/K⁺-ATPase is an integral membrane protein responsible for establishing and maintaining electrochemical gradients of Na⁺ and K⁺ ions across the plasma membrane. These gradients are essential for:

• Osmoregulation
• Sodium-coupled transport of organic and inorganic molecules
• Electrical excitability of nerve and muscle cells

This enzyme consists of two subunits:

1. Alpha subunit – large catalytic component
2. Beta subunit – smaller glycoprotein component regulating assembly and membrane transport

The glycoprotein beta subunit is encoded by multiple genes; ATP1B3 encodes the beta 3 subunit. A pseudogene for this gene exists on chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.