Thermo Fisher Scientific ATP1B3 Monoclonal Antibody (1E9)

Applications

• ELISA (ELISA)
  Tested Dilution: 3 ng/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MTKNEKKSLN QSLAEWKLFI YNPTTGEFLG RTAKSWGLIL LFYLVFYGFL AALFSFTMWV MLQTLNDEVP KYRDQIPSPG LMVFPKPVTA LEYTFSRSDP TSYAGYIEDL KKFLKPYTLE EQKNLTVCPD GALFEQKGPV YVACQFPISL LQACSGMNDP DFGYSQGNPC ILVKMNRIIG LKPEGVPRID CVSKNEDIPN VAVYPHNGMI DLKYFPYYGK KLHVGYLQPL VAVQVSFAPN NTGKEVTVEC KIDGSANLKS QDDRDKFLGR VMFKITARA

Target Information

The protein encoded by this gene belongs to the family of Na⁺/K⁺ and H⁺/K⁺ ATPases beta chain proteins, and to the subfamily of Na⁺/K⁺-ATPases.
Na⁺/K⁺-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for:

• Osmoregulation
• Sodium-coupled transport of organic and inorganic molecules
• Electrical excitability of nerve and muscle

This enzyme is composed of two subunits:

1. Large catalytic subunit (alpha)
2. Smaller glycoprotein subunit (beta)

The beta subunit regulates the number of sodium pumps transported to the plasma membrane through assembly of alpha/beta heterodimers.
The glycoprotein subunit of Na⁺/K⁺-ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. A pseudogene for this gene exists on chromosome 2.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.