Thermo Fisher Scientific KIR3DL1 Polyclonal Antibody
Thermo Fisher Scientific의 KIR3DL1 Polyclonal Antibody는 Human 및 Mouse에 반응하며 Western blot에 적합합니다. Rabbit IgG 기반으로 항원 친화 크로마토그래피로 정제되었고, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human KIR3DL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720356 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
KIR3DL1 (Killer cell immunoglobulin-like receptor 3DL1) belongs to the KIR family, which consists of transmembrane glycoproteins expressed on natural killer cells and subsets of T cells.
KIR genes are polymorphic and clustered on chromosome 19q13.4 within the leukocyte receptor complex (LRC).
KIR proteins are categorized by the number of extracellular immunoglobulin domains (2D or 3D) and by the length of their cytoplasmic domain (L for long, S for short).
Proteins with long cytoplasmic domains mediate inhibitory signals via ITIM motifs, while short-domain proteins associate with TYRO protein tyrosine kinase binding protein to transmit activating signals.
Ligands for several KIR proteins are subsets of HLA class I molecules, playing a crucial role in immune regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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