Thermo Fisher Scientific Human MATN3 Synthetic Peptide
Human MATN3 단백질의 중심부 13개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-20727 항체의 블로킹 펩타이드로 사용 가능. 인간 시료에 반응하며, PBS(pH 7.2) 내 0.1% BSA와 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the center of human MATN3.
PEP-0841 can be used as a blocking peptide with polyclonal antibody PA5-20727.
Target Information
Matrilins (MATNs) are a family of non-collagenous extracellular matrix (ECM) proteins with four known members. They play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs).
MATN1 and MATN3 are specifically expressed in cartilage and are among the most up-regulated ECM proteins during chondrogenesis.
MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain, whereas MATN1 has two vWFA domains separated by one EGF-like domain.
Both MATN1 and MATN3 may modulate chondrogenesis during chondrocyte differentiation. Mutations in MATN3 are associated with various inherited chondrodysplasias.
Aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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