Thermo Fisher Scientific Human ACVR1 Synthetic Peptide
인간 ACVR1의 아미노 말단 근처 14개 아미노산 서열로 구성된 합성 펩타이드. 항체 PA5-20604의 블로킹 펩타이드로 사용 가능. 액상 형태로 PBS 버퍼에 0.1% BSA 및 0.02% sodium azide 포함. -20°C에서 보관. 연구용 전용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the amino terminus of human ACVR1.
PEP-0724 can be used as a blocking peptide with polyclonal antibody PA5-20604.
Target Information
Activin A receptor, type I (ACVR1) belongs to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.
ACVR1 signals a specific transcriptional response in concert with activin type II receptors.
The ACVR1 gene encodes activin A type I receptor, which signals a particular transcriptional response in concert with activin type II receptors.
Mutations in ACVR1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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